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Nodularin-triggered apoptosis and hyperphosphorylation of signaling proteins in cultured rat hepatocytes. Double strand breaks and cell-cycle arrest induced by the cyanobacterial toxin cylindrospermopsin in HepG2 cells. B type natriuretic peptide--a diagnostic breakthrough in peri-operative cardiac risk assessment? Determination of the carbohydrate composition of mammalian glycoproteins by capillary gas chromatography/mass spectrometry. Hepatic sarcoidosis mimicking cholangiocellular carcinoma: A case report and literature review.

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A single-blind, randomized clinical trial of 165 participants with PTSD and alcohol dependence conducted at the University of Pennsylvania and the Philadelphia Veterans Administration. Again, a general analytical expression is derived for the relaxation of surfactant adsorption and surface tension, whose long- and short-time asymptotics are deduced.

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Research regarding timing of surgery and surgical outcome continues to be debated. The substrate-bound type 2 copper site of nitrite reductase: the nitrogen hyperfine coupling of nitrite revealed by pulsed EPR.

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Here, we further showed that incubation of BV-2 cells with DHEA under glucose deprivation (G0) led to dose- and time-dependent decrease in cellular ATP levels. Taken together, these data reveal that alternative RNA splicing may modulate the alpha(1A) calcium channel properties during development. Tuning uranium-nitrogen multiple bond formation with ancillary siloxide ligands. Mitochondrial DNA methylation as a next-generation biomarker and diagnostic tool.

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The velocity waveforms of eye-in-head saccades showed a skew ratio (acceleration period/saccade duration) that varied as a function of saccade size and duration. Effects of pulsed electric fields on inactivation and metabolic activity of Lactobacillus plantarum in model beer.

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Cold debriefing, where individuals or teams are provided with feedback sometime after the event, is associated with improvements in process and patient outcomes. The global exponential stability is analyzed for a class of high-order Hopfield-type neural networks with time-varying delays. Here, we present a novel kind of inverse opal hydrogel particles as the enzymatic carriers. The aim of this study was to evaluate anti-osteoporotic therapies recorded in general practitioner databases in the area of Rome, which used the same computerized medical record management.

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Sfr13, a member of a large family of asymmetrically localized Sfi1-repeat proteins, is important for basal body separation and stability in Tetrahymena thermophila. So far, a wide range of the mutations along the length of RB1 gene have been reported.

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Effect of continuous cold exposure on nocturnal body temperature of man. The control and prevention of tuberculosis occurring in inmates of penal institutes and reformatories.

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The transfer of care and the increasing number of older adults, often with a variety of complex health problems, call for development of the new role in this context. The aim of this study was to evaluate left ventricular (LV) twisting function by three-dimensional speckle tracking echocardiography (3D-STE) in patients with lymphoma after anthracycline therapy.

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The nonpeptide bradykinin B2 receptor antagonist or the NO synthase inhibitor reduced the prevention of intimal thickening by combined temocapril and CS-866. Insulin resistance predicts the progression of abnormal glucose metabolism, which is the main cause of atherosclerotic cardiovascular disease. These cytokines may play a role in regulating the physiological, pathophysiological and oncogenic processes of the ovary. In summary, these data provide evidence that there are seasonal and differential changes of the three GnRHs during this final reproductive period suggesting specific roles for each of the GnRHs in male and female reproduction. Cases of extravesical termination of the ureter in the female urethra

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We report a rare case of an 84-year-old woman who presented with delayed, complete rupture of superficial (flexor digitorum superficialis) and deep flexor tendons (flexor digitorum profundus) of the third, fourth and fifth digits of the right hand in zone V of the flexor tendons. Such a replication mechanism differs from the one that creates tandem repeats by producing short complementary sequence on the same strand of DNA. Poisson mixed effects model was used to adjust for clustering within clinics and covariates.

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The TeTx inhibition was associated with a persistent activity-dependent depression similar to that in control cells. We tested whether culture of bovine embryos with CSF2 alters fetal development and alleviates abnormalities associated with in vitro production (IVP) of embryos. A C5C6 lesion was present in 2 patients, a C5C6C7 lesion in 8 patients and a C5 to T1 lesion in the remaining 8 patients.

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Our studies reveal that recombinant MIF induces cyclin D1 expression in a Rho-, Rho kinase-, MLC kinase-, and ERK-dependent manner in asynchronous NIH 3T3 fibroblasts. Polarimetric heterodyning fiber laser sensor for directional acoustic signal measurement. Use of capsular augmentation enables preservation of the donor-tissue blood supply with local tissue transfer, without adding significant complexity to the procedure or significant donor-site morbidity. Accordingly, the study used a thermogravimetric analyzer to monitor the different states and complex transitions that occurred in the biomass as the temperature varied.

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Unravelling of the protective immunity acquired during a natural infection may contribute to vaccine development. The objective of this study was to clarify the characteristics of myxoma patients who had constitutional signs. Three aims are integral to effective correctional health: patient safety, population health, and human rights.

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Transcription factor Sp1 is localized in the nucleus and regulates gene expression. An insight into the lignin peroxidase of Macrophomina phaseolina. How effective is the application of topical fluoride varnish in preventing dental caries in children?

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Mainstem methods of achieving lung separation are either via a double-lumen endotracheal tube or placing a bronchial blocker (BB) through a single-lumen endotracheal tube. This paper reviews our experience of patients with posterior fossa stroke via observation of pathological eye movements over the past 10 years. Only very few studies are available in the literature that describe the clinical and histomorphological spectrum of the disease.

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Twenty-six non-treatment-seeking moderate-to-high risk gamblers and 26 non-problem gamblers community-recruited via the Internet. Are high-quality mates always attractive?: State-dependent mate preferences in birds and humans.

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Vasodilation and glomerular binding of adrenomedullin in rabbit kidney are not CGRP receptor mediated. The levels of ROS also increased following treatment with the cytokines and MDP and PMA. A common outcome, loss of teeth, usually becomes evident from the fourth decade onwards.

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Aqueous from eight normal and two diabetic patients was analyzed. Purvalanol B and the related compound aminopurvalanol A selectively inhibit TgCK1alpha, confirming the existence of potentially exploitable structural differences between host and parasite CK1 enzymes. Sexually transmitted diseases in HIV-infected subjects are correlated with neurocognitive impairment through an unidentified mechanism. The C-type oxidases (cbb3 cytochromes), which are widespread among pathogenic bacteria, are the least understood. On the other hand, valproate had no effect on overall melatonin secretion or dim light melatonin onset.

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Decreasing the duration of antimicrobial therapy is an attractive strategy for delaying the emergence of antimicrobial resistance. These results demonstrate that parasite-secreted AaaH2 TH is neither necessary for the generation of risky behaviour nor for the increased trappability observed during chronic Toxoplasma infection. Of the 284 patients who were initially HHV-8-seronegative and who received transfusions, 2 seroconverted, 1 with a postsurgery antibody titer of 1:160 and the other with a titer of 1:1280. The difference between the parameters of operated and non-operated sides and also between patients and normal subjects was evaluated by use of a two sample t test (p-value was 0.05). The accelerated blood clearance (ABC) phenomenon accounts for the rapid systemic clearance of PEGylated nanocarriers upon repeated administrations.

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Functional consequences and response to memantine treatment were investigated in vitro and eventually translated into patient care. Patients 65 years or older were enrolled in the study from November 2006 through February 2007. RSV-specific IgA was found in two samples, and RSV-specific IgG in one sample. CSP abnormalities were present in 17 patients of whom all, but 1 presented with intramedullary magnetic resonance imaging hyperintensity. Effects of reoxygenation on repair of potentially lethal radiation damage in cultured MG-63 osteosarcoma cells.

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The aim of this study was to evaluate the usefulness of the collimator detector response (CDR) recovery and the effective scatter source estimation (ESSE) method which is the scatter correction method built into the ordered subsets expectation maximization (OSEM) method. While MEC contains subsets of identifiable functionally defined cell types, recent work employing unbiased statistical methods and more diverse tasks reveals unsuspected heterogeneity and adaptivity in MEC firing patterns. BDI - Beck Depression Inventory, CI-Confidence Intervals, GSES - General Self-Efficacy Scale, HbA1c - glycated hemoglobin, OR- Odds Ratio, PDQOLQ - Parental Diabetes Quality of Life Questionnaire, T1D - type 1 diabetes.

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A normal range of Sb2M values, established by a nonparametric statistical method, was 1.05 to 3.9 mg/mL, with the upper limit being higher than that reported elsewhere. In patients undergoing rhinoplasties that may be prolonged due to other concomitant cosmetic procedures, aseptic preoperative preparation and careful monitoring for signs of orbital infection are recommended. The viral E1B-55K/E4orf6 ubiquitin ligase is also required for efficient viral late protein synthesis in many cell types, but the mechanism is not understood. There is growing evidence that the anti-tremor effects of DBS for ET are directly related to modulation of the dentatorubrothalamic tract (DRT), a white matter pathway that connects the cerebellum, red nucleus, and ventral intermediate nucleus of the thalamus.

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Xenopus cytoskeletal actin and human c-fos gene promoters share a conserved protein-binding site. A simple method for multi-residue analysis of pesticides by low-pressure gas chromatography-tandem mass spectrometry (LP-GC-MS-MS) has been validated in compost samples. The combination therapy of etanercept/MTX greatly improves life quality in AS patients. The four lifestyle risk factors tended to cluster in specific multiple combinations.

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However, compared with placebo, short-term vitamin D supplementation had no discernible effect on a simple measure of physical performance. A multicenter, prospective clinic registry, the American College of Surgeons National Surgical Quality Improvement Program, was queried for Current Procedural Terminology codes representing the most common shoulder and knee arthroscopic procedures.

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Thus, genetic testing at the time of diagnosis is increasingly considered an option for such patients. Impact of silver nanoparticles and silver ions on innate immune cells.

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This design aims at minimal invasiveness and low mechanical irritation during prolonged use, while the chitosan matrix ensures the implant is stiff enough for practical handling during the implantation procedure and dissolves afterwards. Antagonism of ventricular arrhythmias induced by digitalis--a neural phenomenon. In IMR group, as compared to the controls, A3, AL, PL, BL as well as BL/A3, AL/A3, PL/A3 ratios and Th were significantly increased, conversely, h and LV EF was significantly decreased. There was no change in plasma immunoglobulin concentrations and no difference in specific antibody titres following injection of keyhole limpet haemocyanin (KLH) at 10, 20 and 40 days of age. Baumeister and colleagues underline that individual identification and differentiation of selves are important characteristics for group performance.

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Usually it requires that a photosensitizer be added to the drug-delivery system to photochemically destabilize the endosomal membrane. Recently, vendors have started offering metal artifact reduction (MAR) techniques. These findings suggest the presence of a synergistic effect among the plant components. Taken together, our data suggest the absence of arginine methylation of STAT1 and STAT3.

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Nearly all of the respondents expressed desires for sustainable employment and fiscal and social independence. The major compressive element in patients with TOS-associated pain appeared to be the first rib. Therefore, indices of HBS formulated from experimentally derived models of human growth are superior to customary geometric similarity-based indices for characterizing HBS in children during the formative growth years. This could have implications for the health of sponges or for the production of bioactive compounds by sponges in cases where these compounds are produced by symbiotic bacteria rather than by the sponges themselves.

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The strict cosegregation of these markers with a low C1 inhibitor level supports the conclusion that a defective structural gene is responsible for the disease. We use a coarse-grained approach, which represents the system as a network of stochastic (binary) promoter and (continuous) protein variables. We did not observe any detrimental effect associated with the lack of Nrf2 in two different mutant hSOD1 animal models of ALS. Apelin is an adipokine which plays a role in the regulation of glucose homeostasis and may contribute to the link between increased adipose tissue mass and obesity related metabolic diseases.

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Finally, we contrast the effects that acute and chronic IOP elevation can have on the rodent ERG. The goal of this study is to investigate the pharmacokinetic behavior of escin Ia in rats after low, medium and high-dose intravenous administration. Our measurements reveal a further enhancement of convection with inclined boundaries, which suggests that sloping formations provide improved sites for CO(2) storage. Product binding and role of the C-terminal region in class I D-fructose 1,6-bisphosphate aldolase. borchii cryopreserved mycelium, the lag-phase lasted for 6-42 days but no differences in growth curve evolution, growth rate and hyphal morphology were observed except for hyphal growth unit.

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Fatal traffic accidents in the South Moravian Region during 1964-1974 and their social consequences We have developed a practical model for individualising the risk of short-term readmission for CHF. The methodology developed with inductively coupled plasma spectrometry for the determination of marker elements (Al, Si, Ti, Zr, Y, Cr, La, Ce, Cr, and Nd) for childhood soil ingestion in biological (feces), environmental (dust and soil), and food samples are described. These effects require an intact communication between corneal epithelia and fibroblasts.

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It was anticipated that the more resistant nature of human skin would lead to a number of substances being classified as non-corrosive, contrary to historical in vivo animal data. However, many of these differences were less pronounced when taking risk for recidivism into account. An integrating conceptualisation of evidence-based practice that includes a linked process including planned and targeted systematic reviews and guideline development for decision making is needed to facilitate knowledge development and use.

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The genome of KX-V237 comprised two circular chromosomes (3.3 and 1.9 Mb), similar to the structure of the AQ4673 genome. However, given appropriate training and supervision, there is potential for public-private mix for DOTS implementation in this setting. Alignment statistics of active and passive scalar gradients in turbulent stratified flames. The effect of resin-based sealers on fracture properties of dentine. Effect of kilning on the antioxidant and pro-oxidant activities of pale malts.

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Before antibiotic treatment is started the doctor should consider liver and kidney function, a possible malnutrition, interaction with other drugs (especially inhibitors of platelet aggregation and warfarin derivatives), and other diseases of the patient that also prolong bleeding time. Haemaphysalis centropi, a new species of tick from birds in the Far East. Child prostitution: reaching out to children who sell sex to survive. The impact of agricultural runoff on stream benthos in Hong Kong, China. angiotensin II and angiotensin-(1-7), that have differential effects on mesenchymal stem cells, haematopoietic progenitor cells and endothelial progenitor cells.

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The usefulness of the TGUGT and G8 score in daily practice seems to be limited. Equal contributions and credit: an emerging trend in the characterization of authorship in major anaesthesia journals during a 10-yr period.