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A formal definition of MRT, based on excretion of drug molecules and amount of drug, a parameter which is independent of constancy of both clearance and volume of distribution, is introduced and compared to other existing definitions of MRTs, that is, MRT for the two-compartment model, MRT for the stochastic model, and MRT based on amount in the body. The proposed method is effectively applied to two-dimensional mapping of the painting thickness distribution for single-layer and multilayer paint films. Bronchial asthma was induced in mice by intraperitoneal sensitization and inhalation challenge with ovalbumin.

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What does brain imaging tell us about the predisposition to suicidal behavior. We report here the sixth case, in which positivity for lysozyme was also observed for the first time. A clinical series of 22 individuals undergoing staged, bilateral DBS for treatment of essential tremor. The grid technique of radiotherapy with depth dose measurements.

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Retrospective-longitudinal study of 172 PCNL performed in La Ribera Hospital between January 2005 and December 2011, analyzing their bleeding complications and the treatment provided for resolution. Vitamin D3 supplementation increases insulin level by regulating altered IP3 and AMPA receptor expression in the pancreatic islets of streptozotocin-induced diabetic rat.

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The consensus methodology was applied to evidence-orphan issues. The discipline of nursing is on a slippery slope with regard to the ever increasing lack of nursing theory in its work.

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These magnetic measurements can be obtained reliably and inexpensively by simple pickup coils located around the imaged cross section. Units of human whole blood (WB) and RBCs were spiked with high-speed supernatants of 263K scrapie-infected hamster brain homogenates. Older adults, however, displayed greater verbal ability compared to young adults irrespective of a past history of music training. Good preliminary postoperative outcomes have been achieved in patients with Chiari I malformation (without syringomyelia) after using a dura-splitting technique.

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Chagas disease is the main cause of cardiomyopathy in endemic regions of Latin America. Awareness of kidney disease among US adults: Findings from the 2011 behavioral risk factor surveillance system.

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To investigate the expression features of glypican-3 (GPC-3) and its diagnostic and differential values in hepatocellular carcinoma (HCC). Acute inferior myocardial infarction (MI) often induces transient sinus bradycardia through vagal enhancement, known as Bezold-Jarisch reflex, which is explained by preferential distribution of vagal nerve in the inferior wall. Diabetic cardiomyopathy: concept, heart function, and pathogenesis It opens avenues for the design of new vaccines and nutraceuticals that are mandatory for the sustained supply of poultry products in the expanding human population. RANKL binds to its functional receptor, receptor activator of NF-B (RANK), expressed as a transmembrane heterotrimer on the surface of hematopoietic osteoclasts progenitors and mature osteoclasts.

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Introduction of Integrative Health and Acupuncture to Pre-Clerkship Medical Students. Data on caries experience (number of decayed, missing and filled tooth surfaces) and occlusal traits (using Dental Aesthetic Index) were collected for each child.

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Higher vitamin D status, but not FGF21, was associated with greater postprandial glucose oxidation and improved insulin sensitivity. We aimed to investigate the incidence and predisposing factors of iodinated CM-associated bowel angioedema during computed tomography (CT) examinations. Electrophysiological and behavioral responses were recorded in healthy young (19-23 years) and older (56-66 years) subjects during the execution of a visuospatial attention task. The model predicts that if cell division and death rates are dependent on the density of cells in a population, a predictable cycle between short and long filament lengths is produced. Abstracts will be submitted to national and international conferences.

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Other methods estimating surgical prevalence, backlogs in treatment, and disability incurred by delays in care may provide more practical approaches to disease burden that can be useful tools for clinicians and health advocates. However, it is clinically similar to other inflammatory enteropathies, which result from both host and environmental triggers, and for which immunomodulation is a cornerstone of therapy. Nevertheless, these projects have provided a plethora of material that will aid in understanding the biology and evolution of these parasites, as well as identifying new targets that can be used to design urgently required drug treatments for the diseases they cause.

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The formation of the DT is dependent on nucleotide binding, while formation of the DH also requires hydrolysable ATP. The present study aimed to present the psychometric properties of this scale.

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A total of 63 patients were recruited and randomly assigned to clozapine group or risperidone group using computer-generated random number tables. Fibromyalgia is a rheumatologic disorder associated with somatic and psychologic conditions.

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Recent studies have shown that inadequate vitamin D levels are associated with a poor cancer prognosis, but data regarding actual vitamin D levels in cancer survivors are limited. Simplified formulae for estimation of MPA-AUC in tacrolimus (Tac) group or cyclosporin A (CsA) group were established by multiple stepwise regression analysis. Ellipsoidal Polyaspartamide Polymersomes with Enhanced Cell-Targeting Ability.

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Our data suggest that the combination of aspirin and CDDP exhibited a higher degree of toxicity against SGC7901/CDDP cells compared to that of aspirin or CDDP alone. With the heightened interest in the organism as a potential biological threat agent, a large number of interesting detection technologies have recently been developed, including methods involving immunological and nucleic acid-based assay formats.

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Chemokine (C-C motif) ligand 2 (CCL2) participates in different mechanisms contributing to the spinal cord inflammation and pain development after sciatic nerve injury. Patients who have injuries to the anterior portions of the chest wall should be considered for internal fixation of the chest wall when the injuries are severe and can lead to clinical disability.

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A 51 year-old Caucasian right handed housewife lady (weight 61 kg, height 159 cm) presented with a headache of acute onset which proved to be caused by acute subarachnoid hemorrhage. To develop a protocol for breaking of seed dormancy and increasing the seed germination rate of Bunium persicum. However, whether helical hairpins direct spontaneous insertion of TetA or are required instead for its interaction with the cellular secretion (Sec) machinery is unknown. Between November 1988 and May 1992, 14 patients were enrolled in a pilot study to evaluate the feasibility and results of hyperfractionated reirradiation for the treatment of head and neck recurrences or of second primary tumors developed in a previously irradiated volume.

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Adult-derived mesenchymal stem cells have received considerable attention over the past two decades for their potential use in tissue engineering, principally because of their potential to differentiate into multiple stromal-cell lineages. Tumor was composed of monotonous, uniform cells which have oval-round nucleus, perinuclear halo, and indistinct cytoplasm.

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The intra-operative examination of the bile ducts with the cholangioscope Sensitised and control animals were then challenged for 60 minutes with an aerosol of the same antigen, which also contained the electron dense pore marker lanthanum. Cross-sectional study of 1210 consecutive HIV-infected adults followed in HIV outpatient unit (Montpellier/France). Also, elevated ACE activity in a patient with otherwise typical MS need not raise suspicions of alternative diagnoses.

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Complex C(sp(3))-rich polycyclic molecules containing up to 8 stereocenters can be readily formed via an operationally simple two-step procedure. Because of financial and other limitations, most feasible evaluation methods will not have the power to detect changes attributable to the intervention nor to provide confidence that there was no important change. The rise of the color threshold was more remarkable as the test wavelength was more close to the peak wavelength for rod sensitivity. Retrospective design, lack of control group, small sample population. The effect of ammonia on the alanine metabolism was investigated in perfused rat liver.

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Leptin levels in women with polycystic ovaries undergoing ovarian stimulation: relation to lipoprotein profiles. The activity cliff concept has experienced increasing interest in medicinal chemistry and chemoinformatics. The 3 factor-derived syndromes identified among Gulf War veterans appear to represent variants of a generalized injury to the nervous system. Significance of spontaneous estrogen formation during the menopause

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Relationship between soluble collagen and urinary hydroxyproline in the lathyritic rat. Thirdly, in vivo or in vitro glucoprivation did not affect the activity of RVLM adrenal premotor neurons. We studied whether the compensation could be evaluated by observing OKAN.

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We examined an alternative hypothesis in which these biases are caused by domain-general mechanisms, in which participants overestimate the distance between consecutive localization judgments that are spatially close. Lower levels of chronic inflammation have been associated with improved survival after breast cancer. S(N)1-S(N)2 and S(N)2-S(N)3 mechanistic changes revealed by transition states of the hydrolyses of benzyl chlorides and benzenesulfonyl chlorides.

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Only phenyl-based polymers are nonplanar, but the main contributor to the larger band gap is electronic, not structural effects. Alpers-huttenlocher syndrome: origins of clinicopathologic recognition. The petunia homologue of tomato gast1: transcript accumulation coincides with gibberellin-induced corolla cell elongation.

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This provides completely new possibilities not only regarding the assessment but also for the treatment of forensic inpatients. The incidence of fungal bone and joint dis-ease is increasing with an increase in the prevalence of factors predisposing to invasive fungal disease, such as the use of central venous catheters, broad spectrum antibiotics, immunosuppression, and abdominal surgery. There were 38 patients without PCOS who underwent standard ICSI treatment comprising the control group (control-ICSI).

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Development of a patient safety climate survey for Chinese hospitals: cross-national adaptation and psychometric evaluation. In treating septicaemic conditions of neonatal foals the deficit in serum immunoglobulins should be corrected, and it is advisable to administer antimicrobial agents or combinations that produce a bactericidal effect at dosages modified for immature physiological processes.

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As for in vivo study, elevated level of neutrophils was observed, despite the minimal level of pro-inflammatory cytokines (TNF-alpha, IL-12, IFN-gamma) detected in the bronchoalveolar lavage fluid (BALF) of mice treated with the D-SPM/pDNA complexes. It is characteristic of these symptoms that they appear 1-4 days after reduction of the dose or the last administration of the drug. Although DEAD-box helicases share a highly conserved core domain, the enzymes catalyze a wide range of biochemical reactions. The inactivation of catalase and insignificant glutathione levels marked the onset of oxidative stress. The role of genetic polymorphisms in the promoters of the matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 genes in head and neck cancer.

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CLINICOPATHOLOGIC conference: Bilateral renal cortical necrosis in pregnancy. A study of human papillomavirus on vaginally inserted sex toys, before and after cleaning, among women who have sex with women and men.

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Magnetic resonance imaging (MRI) is important in the early diagnosis of novel or relapsing multiple sclerosis (MS). We analysed potential variables felt to be predictive in the chances of a patient having their procedure as previously scheduled. These results are consistent with the theory that loss of NOS expression may be associated with the progression of breast cancers via increase in motility and loss of adhesion. Furthermore, we propose that the Slo3 channel activation gate lies deep within the pore between F304 in the S6 segment and the selectivity filter. The HEA group received normal saline instead of tranexamic acid in the same manner.

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Extraction and characterization of the smooth-type lipopolysaccharide from Fusobacterium nucleatum JCM 8532 and its biological activities. DNA identification is based on differences in the EPR spectra of mononitroxide-labeled nucleic acids. We now demonstrate that competition also occurs between mitochondrial malate dehydrogenase and mitochondrial aspartate aminotransferase, which does not require a nucleotide for its activity. Differences in epidemiological characteristics of pediatric and adult burns/scalds may have important operational, training and public health implications.

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Software is becoming an increasingly important aspect of medical devices and medical device regulation. Furthermore, delivery of bile pigments, either alone or in combination with CO, presents another avenue for protecting against vascular disease. Excision of HO may be a treatment option to correct limitations in locomotion.