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Arcolane (Ketoconazole)

Arcolane is only found in individuals that have used or taken this drug. It is a broad spectrum antifungal agent used for long periods at high doses, especially in immunosuppressed patients. [PubChem]Arcolane interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary for the conversion of lanosterol to ergosterol. This results in inhibition of ergosterol synthesis and increased fungal cellular permeability. Other mechanisms may involve the inhibition of endogenous respiration, interaction with membrane phospholipids, inhibition of yeast transformation to mycelial forms, inhibition of purine uptake, and impairment of triglyceride and/or phospholipid biosynthesis. Arcolane can also inhibit the synthesis of thromboxane and sterols such as aldosterone, cortisol, and testosterone.

Other names for this medication:
Ketoconazole, Nizoral, Akorazol, Arcolan, Arcolane, Asquam, Biogel, Clarazole, Conazol, Daktagold, Daktarin, Dezor, Diazon, Dikoven, Eumicel, Extina, Funginoc, Fungoral, Ilgem, Kenazol, Kenazole, Ketazol, Ketokonazol, Ketolef, Ketovid, Ketozal, Liondox, Lizovag, Micoral, Micosin, Muzoral, Mycoderm, Noell, Orifungal, Oronazol, Panfungol, Perative, Phytoral, Pristinex, Tiniazol, Tinuvin, Xolegel, Yucomy, Zoloral,

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In this work, we measured gene expression of AR in left heart atria and ventricles in rats exposed to cold stress and in cold-acclimated rats exposed to a novel stressor (immobilization). Paclitaxel-loaded poly(lactic-glycolic) copolymer nanoparticles have been prepared using a precipitation technique.

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Individuals from two workplaces (local health board and steelworks) attended a medical health check with an added CVD and diabetes risk assessment component. Coinfection with Haemophilus influenzae promotes pneumococcal biofilm formation during experimental otitis media and impedes the progression of pneumococcal disease. Factors contributing to the success or failure of skeletal anchorage devices: an informal JCO survey.

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These results suggest that cleavage and inactivation of DNA-PKcs prevents this factor from functioning in DNA repair, recombination or transcriptional regulation during apoptosis. Laryngeal chondrosarcoma is a rare tumor requiring clinical, histologic, and radiographic correlation for definitive diagnosis. Murine genetic deficiency of neuronal nitric oxide synthase (nNOS(-/-) ) and interstitial cells of Cajal (W/W(v) ): Implications for achalasia?

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20 h/E(spl)/hey-related genes were identified in Fugu, which is twice the number of corresponding zebrafish genes known so far. Use of simulated physician handoffs to study cross-cover chart biopsy in the electronic medical record. We conclude that this approach has considerable potential for more efficient use of information in longitudinal modeling of non-monotonic clinical assessment scale data. We tested whether this hypothesis was true for an unselected population of ACS patients with and without DM admitted with non-ST elevation MI or unstable angina, in a non-trial setting over a longer term of follow-up.

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In this study, the distribution of the a1 and a3 chains in both normal and neoplastic lung tissues has been examined by immunohistochemistry, using specific monoclonal antibodies. We evaluated the relationships between the RDW and the high-sensitivity C-reactive protein (hsCRP) N-terminal pro-brain natriuretic peptide (NTpro-BNP), fasting blood glucose and lipid levels, as well as other parameters of blood examinations and angiographic manifestations. The experimental animals were either exposed for 4 hours per day to broadband noise at 122 dB SPL (A-weighted) for 2 consecutive days or perfused cochleae with 5 mg/ml of the SIN1 solutions, an exogenous NO and superoxide donor, for 30 minutes.

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Intracranial plaque characteristics are associated with stroke events. In all systems, lumen formation involves the structured expansion of the apical plasma membrane through general mechanisms of vesicle transport and of microtubule and actin cytoskeleton regulation. This process may involve the sclera but also the cornea, adjacent episclera, and underlying uvea and therefore threaten vision.

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Fundus photographs before and after vitrectomy due to a macular hole or epiretinal gliosis were compared and drusen arrangement in the peeling site was analyzed. Early glottic cancer can be cured with transoral laser resection, but in cases with anterior commissure involvement, there is still controversy concerning the best treatment modality.

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In-hospital mortality was analyzed to evaluate the predictive value of the Japanese severity score. Should male gender assignment be considered in the markedly virilized patient With 46,XX and congenital adrenal hyperplasia? Similarly strong correlations of the mGCC thickness with the FDT sensitivity in the SAP normal and SAP abnormal halves, but not with the SAP sensitivity, indicates that the mGCC thickness and the FDT sensitivity may be more optimal structure-function indicator in preperimetric stage of glaucoma. Objective and subjective refraction were performed followed by Orbscan imaging. Frailty is associated with an increase in the rate of mortality, hospitalizations and dependence in basic activities of daily life.

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Combination of sirolimus and sorafenib appears to have synergistic effect when treating HCC in preclinical settings. This retrospective comparative study included 22 patients (22 eyes) who underwent pars plana vitrectomy with membrane peeling for the treatment of idiopathic epiretinal membrane. How does our brain make a decision on whether to take a risk or to play it safe?

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Original and review articles published by the author were reexamined for evidence of gene-gender interactions. Implementation of Medicaid Managed Long-Term Services and Supports for Adults With Intellectual and/or Developmental Disabilities in Kansas. All the herds in the material had an average cell count of 680,000/ml. Former University of British Columbia family practice residents who trained in Vancouver, BC, including residents who participated in a procedural skills workshop in 2001 or 2003 and residents graduating in 2000 and 2002 who did not participate in the procedural skills workshop.

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Gangliosides in vivo reduce diabetes incidence in non-obese diabetic mice. vivax infected individuals and open perspectives for the rationale of malaria vaccine designs capable to sustain high levels of IgG3 against polymorphic malaria antigens. Systemic lupus erythematosus (SLE) poses a growing challenge for healthcare systems, affecting an increasing number of people in Korea. Taxol can also be semisynthetically produced via the conversion of baccatin III or 10-deacethylbaccatinIII found in Taxus needles but the cost and difficulty of the extraction process of the semisynthetic precursors are also very high.

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Fetal brain MRI textural patterns were associated with neonatal neurodevelopment. Hyperparasites of the genus Ampelomyces on powdery mildew fungi in Serbia. For physical rehabilitation in the ICU, is it early to bed, early to rise? The main idea of the algorithms is to evaluate and select feature subsets based on their capacities to reproduce sample projections on principal axes. A new method called Off-Axis Integrated Cavity Output Spectroscopy (OA-ICOS) has been developed which requires extremely low-energy consumption and neither reference gas nor cryogenic cooling.

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Hyperammonemia is one of the rare nevertheless serious side effects associated with valproic acid treatment. Tibiae and femora from Ebf1(-/-) mice had a striking increase in all bone formation parameters examined including the number of OBs, osteoid volume, and bone formation rate. Pharmacologically isolated GABA(A) receptor-mediated IPSCs are decreased in the two partial nerve injury models compared with naive animals. The participants wish to take care of themselves, so they do not become a burden for society and the local authorities. Part of the capillary was filled with the optimal buffer for the enzyme reaction, whereas the rest was filled with the background electrolyte optimal for the separation of substrates and products.

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Fluoroscopy-based 3-D reconstruction of femoral bone cement: a new approach for revision total hip replacement. In the present work, we discuss three models for simultaneously describing scattering, spectral, and polarization characteristics of scarab beetles. Patients with elevated serum CK-MB often suffer from cardiac insufficiency, severe illness status, and have high mortality. Effects of different transfusion on intraoperative blood loss and postoperative drainage volume in posterior lumbar spinal surgery

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The biological activity of penichromin, a pigmented material produced by P. The mental health of mothers in and after violent and controlling unions.

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The purposes of this study were to investigate the effect of laser irradiation on the adhesion of brackets bonded to feldspathic porcelain and to compare it with brackets bonded with conventional techniques. Interventions to improve aerobic capacity or decrease energetic cost of walking may prevent slowing of gait speed and promote mobility in older adults. The variance of the velocity exhibits parabolic-like variation across the capillary. Structural transition from supercoiled form to open circular form of plasmid DNA were observed in the presence of nine irradiated-photosensitizers, however DNA damage by six phototoxic and five nonphototoxic drugs were negligible or weak even though some chemicals exhibited significant generation of ROS.

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This retrospective study explored 56 patients undergoing tumor resection for malignant progression after previously treated IDH1-mutated WHO grade II astrocytoma. An immunohistochemical study of androgen receptor in carcinoma arising in pleomorphic salivary adenoma. Accuracy of diabetes diagnosis in health insurance claims data in Taiwan. Results of natural variations of mastication on the interpretation of test results

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Bioinformatics analysis of transcriptome dynamics during growth in angus cattle longissimus muscle. Calcitonin gene-related peptide (CGRP) and substance P (SP) in dual labeled cells were determined by immunohistochemistry, giving possible insight into the cause of pelvic pain. Cerebral involvement was confirmed by magnetic resonance imaging and histologic examination of brain sections after hematoxylin-eosin-safran or silver staining.

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We analyze characteristics of body-layer vibration based on the measurements from designed experiments. Vitamin status was affected by alcohol, nicotine and contraceptives. The coagulation dynamics could be well described using the Arrhenius formalism with the activation energy of 106 kJ/mol and the frequency factor of 1.59 x 10(13)/second.

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