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Expal (Spironolactone)

Expal is a potassium-sparing diuretic that removes excess fluid from the body in congestive heart failure, cirrhosis of the liver, and kidney disease. It also can be used in combination with other drugs to treat diuretic-induced low potassium (hypokalemia) and high blood pressure. Expal also is used to counteract the effects of excessive adrenal aldosterone production (hyperaldosteronism) that can occur from a tumor in the adrenal gland or enlarged adrenal glands (hyperplasia of the adrenal glands). Expal and its active metabolites are specific pharmacologic antagonists of aldosterone, acting primarily through competitive binding of receptors at the aldosterone-dependent sodium-potassium exchange site in the distal convoluted renal tubule. Expal causes increased amounts of sodium and water to be excreted, while potassium is retained. Expal acts both as a diuretic and as an antihypertensive drug by this mechanism. It may be given alone or with other diuretic agents that act more proximally in the renal tubule.

Other names for this medication:
Spironolactone, Aldactone, Aldactazide, Aldactazine, Aldazida, Aldazide, Aldozone, Alexan, Alizar, Carpiaton, Espirone, Espironolactona, Expal, Kespirona, Lanx, Letonal, Osiren, Osyrol, Practon, Prilactone, Spiractin, Spiresis, Spirix, Spiroctan, Spirolang, Spirolon, Spiron, Spirono, Spironolacton, Spironolactona, Spironolakton, Spironolattone, Spirotone, Verospiron, Xenalon,

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Valosine, Sarotena, Levocine, Probitor, Tolerade, Omeprol, Primotren, Dicorate, Zithromax, Daclin, Zydalis, Cyclovex, Warfarine, Klavocin, Clavet, Eryn, Zymycin, Citaxin, Overal, Spironolactona, Marivarin, Norwin, Sizodon, Klindan, Leflumax, Barazan,

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Meta-analysis of branched chain amino acid-enriched nutrition to improve hepatic function in patients undergoing hepatic operation Autoantibodies against cyclic citrullinated peptide (anti-CCP) are considered to be a sensitive and specific marker for rheumatoid arthritis (RA). Evaluation of four molecular assays for detection of pandemic influenza A (H1N1) 2009 virus in the routine diagnostic laboratory. Theoretical investigations of the time-resolved photodissociation dynamics of IBr(-). Instability of spatial encoding by CA1 hippocampal place cells after peripheral nerve injury.

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Sparsity constrained split feasibility for dose-volume constraints in inverse planning of intensity-modulated photon or proton therapy. We examined HGFA immunolabelling in the brains of neurologically normal and Alzheimer disease (AD) cases. In the newly designed stimulator, electromyography feature extraction and feedback control were used to intelligently control the rehabilitation treatment.

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Electronic resistance switching in the Al/TiO(x)/Al structure for forming-free and area-scalable memory. Some particles involved in the regulation of an immune system might represent prognostic value for B-cell chronic lymphocytic leukemia (B-CLL). Effects of 5-methoxytryptamine derivatives on reserpine-syndrome in mice. Adipose triglyceride lipase and G0/G1 switch gene 2: approaching proof of concept.

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Effects of mitochondrial DNA rate variation on reconstruction of Pleistocene demographic history in a social avian species, Pomatostomus superciliosus. Despite modern advancements in surgeries, chemotherapies, and radiotherapies over the past few years, lung cancer still remains a very difficult disease to treat.

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we used real-time quantitative PCR to examine the gene expression profiles in cumulus cells acquired from older and younger age groups. We propose a model which includes these two types of indicators and show that they behave in markedly different ways. Osteogenic differentiation of periodontal fibroblasts is dependent on the strength of mechanical strain. Acute delta9-tetrahydrocannabinol-induced deficits in reversal learning: neural correlates of affective inflexibility. Action of canavanine on the synthesis of RNA in Escherichia coli

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Planum temporale asymmetry to the right hemisphere in first-episode schizophrenia. Here we show that in the rat lateral amygdala transient receptor potential channels mediate an excitatory synaptic response to glutamate. Recent data have highlighted a new population of innate lymphoid cells, activated by these two cytokines, and mediating type 2 innate immunity dependent asthma. These results suggest that the increase in endotoxin-binding capacity of HDL may serve as a protective mechanism against endotoxin in chronic ethanol-loaded rats. Transurethral resection of the prostate, though it is the surgical standard of reference, is not free from complications such as reabsorption syndrome, bleeding, or even blood transfusion in a percentage of cases.

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Matlab, BSR and exponential smoothing were employed to develop and evaluate a model for risk classification as well as to forecast plague epidemics at the Spermophilus Dauricus Focus. Evidence-based recommendations for screening, prevention, and early intervention should be implemented to improve quality of life and decrease comorbidities in this population. Cisplatin-induced ototoxicity and the role of pharmacogenetic testing. Magnetic response in cultures of Streptococcus mutans ATCC-27607. An algorithm for detecting T-wave alternans (TWA) based on the maximum of T-waves

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Telomeric Repeat Amplification Protocol (TRAP) assays and RT-PCR (qualitative and realtime) were performed to investigate activity of telomerase as well as expression of human telomerase reverse transcriptase (hTERT) and c-Myc. The authors report 12 cases of induction of labour which was carried out with the help of RU 486 in the 3rd trimester of pregnancy (mean duration of the pregnancy 34.2 weeks). These results demonstrate the functionality of a novel scVEGF-bearing MB contrast agent, which could be useful for molecular imaging of VEGFR-2 in basic science and drug discovery research.

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Susceptibility of Biomphalaria straminea from Peixe Angical dam, Tocantins, Brazil to infection with three strains of Schistosoma mansoni. An institutional review board-approved retrospective review of a prospective, prostatectomy database was performed. Previous work has demonstrated that plasma levels of lactoferrin (LF), a known inhibitor of CSF production, are elevated following burn injury. Two cases are reported of women aged 18 and 36 years respectively who developed a typical picture of hyperthyroidism by Graves Basedow disease (primary hyperthyroidism, diffuse goiter with increased uptake, positive stimulating thyroid antibodies, exophthalmos). The principle of the method is that air-liquid, liquid-liquid, and liquid-cell interfaces produce distinct specular or diffuse reflections that can be imaged to give a micron-resolution replica of the mucosal surface.

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