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Genome-wide association and linkage identify modifier loci of lung disease severity in cystic fibrosis at 11p13 and 20q13.2. The most unfavorable prognostic factor is the presence of distant metastasis at the time of diagnosis.

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This study explored the relative clinical utility of these models in screening for borderline personality disorder (BPD). Bone marrow histology in multiple myeloma: autopsy studies on treated and untreated patients. The tensile characteristics of both cheeks were tested and compared in each group. We report a case of herpes simplex virus (HSV) encephalitis (HSE) in an 11-year-old boy who recovered with acyclovir therapy but developed relapse after 2 weeks. The consequence of a detected mutant was predicted by in silico analysis and confirmed by mRNA analysis.

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MTL was not associated with patient-reported symptoms, but may be associated with a more rapid need for future revision surgery. On-line liquid chromatography coupled with high field NMR and mass spectrometry (LC-NMR-MS): a new technique for drug metabolite structure elucidation. Endothelial dysfunction is associated with increased risk for cardiovascular events in patients with coronary artery disease and may predict in-stent restenosis after percutaneous coronary intervention.

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The ion transport by a modified hopping mechanism was demonstrated by molecular dynamics simulation studies. Role of relative size of asperities and adhering particles on the adhesion force.

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Surgical intervention in the management of severe acute pancreatitis in cats: 8 cases (2003-2007). A set of 32 self-rated depression items from the SDS depression measure and weighted to both melancholic and non-melancholic depressions were analysed for any impact of age in clinically diagnosed melancholic and non-melancholic depressed patients. Among the human herpes viruses, three are neurotropic and capable of producing severe neurological abnormalities: herpes simplex virus type 1 and 2 (HSV-1 and HSV-2) and varicella-zoster virus (VZV).

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The presence or absence of FSD as measured by the Malay Version of Female Sexual Function Index and 5HT2A-1438 G/A (rs6311) SNP. Motor trajectories from 4 to 18 months corrected age in infants born at less than 30 weeks of gestation. Every patient has been interviewed by phone to evaluate outcome. Individual scores for each test (based on severity of findings) and a sum of scores of all three procedures (CCJ score) were evaluated for their potential to measure the need for and improvement after surgery.

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Coronary anatomy was analyzed in computed tomography angiographies of 70 patients to calculate height differences between the catheter tip and different coronary segments in the supine position. Records from all minimally invasive sacral colpopexies performed from 2009 to 2012 were reviewed.

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Air concentrations of 239Pu and 240Pu have been continuously monitored since the accident. Our results indicate a high level of QOL in hearing-impaired children and their families following treatment with either bilateral hearing aids or bimodal stimulation.

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This study evaluated the hepatic toxic effects of prenatal exposure to lead in rats and the possible protective effect of dandelion (Taraxacum officinale) added to the diet. Fibromyalgia syndrome: current concepts in pathophysiology, clinical features, and management. By single-fiber polymerase chain reaction analysis, COX-negative fibers contained a low number of wild-type or duplicated mtDNA molecules (ie, nondeleted). Evidence that hybrid polar compounds have therapeutic potential for cancer treatment is also reviewed. The South Dakota Model: Health Care Professions Student Disaster Preparedness and Deployment Training.

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A study of fetal intrathoracic pressures during labor and delivery. Our data demonstrate that use of the wound VAC is a safe approach in the management of premature infants with NEC requiring surgical intervention with outcomes comparable to standard surgical management. The study used a 2-week daily diary approach to examine same-day and temporal relations between affective symptoms and sexual function. We updated the established NZ ACS Audit group of 36 hospitals to 39 hospitals now admitting ACS patients across New Zealand. Mechanistically, even upon provision of adequate T cell help, Foxo1-deficient GC B cells showed less proliferative expansion than controls.

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Using a novel sparse matrix representation of the Fokker-Planck equation, which describes the ensemble dynamics, we calculate the transmission functions for small modulations of the mean current and noise noise amplitude. The muscle twitch in myofascial pain relief: effects of acupuncture and other needling methods. This substance, which appears to be free of contaminating material, possesses in extraordinary degree the capacity to react with influenza, mumps, and Newcastle disease viruses. Celiac disease is a common, lifelong autoimmune disorder for which dietary control is the only accepted form of therapy.

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However, abnormal reactions to FMIONPs in the brain or spinal cord could be seen if they are combined with CNS injuries e.g., hyperthermia or traumatic insults to the brain or spinal cord. In 2 of the 13 metastasis-free patients deposits of lethal outcome had formed, survival time averaging 27 months. An interdisciplinary approach to the assessment and behavioral treatment of urinary incontinence in geriatric outpatients UCSF gene discover opens new window on mechanism of yeast infection. The Mason-Pfizer monkey virus (M-PMV) Gag protein follows a morphogenesis pathway in which immature capsids are preassembled within the cytoplasm before interaction with and budding through the plasma membrane.

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A comparison of psychologically-induced cardiovascular reactivity in laboratory and natural environments. To assess the effect of trandolapril (2 mg once daily) and indomethacin (25 mg three times daily), alone and in combination, on renal function and renal functional reserve in hypertensive patients (DBP 95-115 mmHg) requiring regular non-steroidal anti-inflammatory drugs (NSAIDs).

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When feasible, postponing surgery until after chemotherapy is advisable. A study of the role of physical ressons of a wave and magnetic nature on the development of the epileptic process may help to understand the pathogenetical mechanisms of the disorder. Whether these properties are efficacious in reducing VAP is not known. Clinical experiences with the combination preparation sandosten calcium African Americans have historically had high high-density lipoprotein cholesterol (HDL-C) compared with other races and ethnicities.

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To determine the prognostic role of three RBP genes: insulin-like growth factor-binding protein 2 (IGFBP2), RNA-binding motif protein 3 (RBM3), and cold-inducible RNA-binding protein (CIRP) in colon cancer. These findings suggest that nanotopography and HA provide important cues for promoting chondrogenic differentiation of DPSCs.

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Understanding the function of biomolecules is crucially dependent on observing the dynamics of their biosynthesis, distribution, and metabolism in their native environment at the cellular and organismal levels rather than their behavior in the isolated samples. In this study, the serum 25(OH)D status in hip-fracture cases was examined in four regions in Japan. However, the study also underlines that mortality rate is high and therefore treatment options should be well-considered in this high risk group.

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Five compounds of iridoids, lignan and phenylpropanoid glycosides were isolated from the roots of Valeriana jatamansi by column chromatography. The occurrence of this peroxisomal phenotype was cell cycle phase independent, while microtubules were essential for phenotype formation. The methods used were proteomics to measure the protein damage via protein loss after different periods of exposure and mass spectroscopy methods to identify specific marker peptides that are specifically created by this type of damage. The prognosis of AMF-R positive patients was poorer than that of AMF-R negative patients.

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Structural changes in the temporal lobe and piriform cortex in frontal lobe epilepsy. The comparison of 24-hour urinary sodium, albumin, and protein excretion in chronic kidney disease patients with type 2 diabetes mellitus using insulin detemir or insulin glargine. KLK4 cDNA was amplified by reverse transcription-PCR (RT-PCR) and cloned in a pPICZalphaA expression vector. Recombinant alpha 2-interferon in the treatment of B chronic lymphocytic leukemia in early stages.

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Pipetting and dilution are universal processes used in chemical and biological laboratories to assay and experiment. Microspheres afforded high antitumor efficacy without obvious toxic effects to normal organs, owing to its significantly increased MTX tumor retention time, low MTX levels in normal organs and strong photodynamic activity of PLA-phe-C60. Grades 3 and 4, in which the glottis is not visualized, are considered difficult intubations. The native enzyme had a molecular mass of 204 kDa measured by Sephadex G-200 and that of subunit on the SDS-PAGE was found to be 45 kDa.

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Porous one-dimensional Mo2C-amorphous carbon composites, fabricated by in situ solid state reactions, are exhibited as effective and high-performance electrocatalysts towards the hydrogen evolution reaction (HER). For every teenage primigravidae, two subsequent adult primigravidae were correspondingly studied.

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The CD14 surface molecule is predominantly expressed by cells of myeloid origin and regarded as a specific marker for macrophages (M phi). Since DY TME causes disease once it enters the peripheral nervous system, the restriction in DY TME pathogenesis is due to its inability to establish infection in LRS tissues, not a failure of transport. In-space treatment for degenerative lumbar disease is easy and safe, with good early effects.

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New progress in noninvasive method of blood glucose measurement using FT-mid-IR spectroscopy Decline of coronary heart disease mortality in Finland during 1983 to 1992: roles of incidence, recurrence, and case-fatality. In this study, 20 human volunteers received a placebo and atropine doses of 0.5, 1.0, 2.0, and 4.0 mg X 75 kg-1 in a Latin Square double blind design, and effects were monitored for 3 h postinjection. The computed tomography of the head revealed the intracranial multiple calcification lesions, which indicated the symptoms of tuberous sclerosis. Abdominal apoplexy is a rare and fatal emergency event, which is coined as a comparison to the cerebrovascular apoplexy.

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Recordings of CMMCs were made from the isolated murine large bowel, with or without a fecal pellet. Lipid imaging by gold cluster time-of-flight secondary ion mass spectrometry: application to Duchenne muscular dystrophy. The aim of this study was to assess the impact of this practice change.

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We have devised two useful schemes to determine the rf phase of the modulation waveforms in harmonic FM spectroscopy, a novel technique that we reported recently for the removal of residual amplitude modulation. An autologous haematopoietic stem cell, liver and renal transplant recipient was found to be positive for simian virus 40 (SV40).

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Closed intramedullary derotational osteotomy and hip arthroscopy for cam femoroacetabular impingement from femoral retroversion. Evidence for progressive brain abnormalities in early schizophrenia: a cross-sectional structural and functional connectivity study. All patients who underwent any common urological procedure as the primary procedure were selected for analysis.

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Two-year post-transplantation cytomegalovirus DNAemia in asymptomatic kidney transplant recipients: incidence, risk factors, and outcome. Shigella and Salmonella kill host cells and trigger inflammatory responses by mechanisms that are not fully understood. Effect of carbohydrates and polyols on amide content and protein fragmentation in a lactoglobulin preparation