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We analyzed histochemical and MR imaging properties of fiber architectonics and extracellular matrix (ECM) of periventricular areas to disclose the potential significance of topographically specific WM lesions for the neurodevelopmental outcome. Temporal and tissue-specific disruption of LINC complexes in vivo. Uracil DNA glycosylase (UDG) activities in Bradyrhizobium diazoefficiens: characterization of a new class of UDG with broad substrate specificity.

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Mutation analyses in ACVRL-1, bone morphogenetic protein receptor type 2 (BMPR2) and ENG were performed in 14 Chinese Han patients with HHT-associated PH. All 350 cases of late-onset MADD reported in the literature to date have been analyzed and evaluated with respect to age at presentation, diagnostic delay, biochemical features and diagnostic parameters as well as response to treatment. Image standardization based on fat and pectoral muscle signals was necessary for intercase comparisons. Treatment of ring degloving injuries of the finger is one of the most demanding problems in hand surgery.

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Forty-four single nucleotide polymorphisms (SNP) in the FTO gene were tested and analyzed by the VeraCode GoldenGate Genotyping Assay. The number of vascular patients harbouring mycoplasmas in the urine was low and we found no indication for changes in the prophylactic antibiotic treatment based on these findings.

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A systematic literature search with no limits was performed in PubMed and Embase. A simple, relatively fast, coulometric method to determine both the surface-moisture and bound-moisture content of a wide variety of lyophilized, allergenic extracts has been developed.

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An unusual anatomo-pathologic aspects of a case with pseudoxanthoma elasticum. The method was compared with indirect RT-in situ PCR and in situ hybridization for detecting hepatitis C virus (HCV) RNA. Physiological hypertrophy was induced by swimming and the mRNA levels of GATA binding protein 4 (GATA4), atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), endogenous hepatocyte growth factor (HGF), and insulin like growth factor-1 (IGF-1) from the whole heart were determined by real-time polymerase chain reactions (RT-PCRs) analysis.

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A factor able to induce an early local inflammation in rabbit skin was detected in the supernatant of mitogen-stimulated human blood leukocytes. In view of the rising melanoma incidence and the absence of effective treatments for metastatic disease, there is an urgent need for new methods that allow the early detection of melanoma.

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We chose 17 years of age as the cut-off for early-onset schizophrenia spectrum disorders based on a recent clinical consensus. Thus, depression can be considered a strong predictor of death in CHF elderly subjects. To comprehensively evaluate the effectiveness of acupuncture as a treatment for fibromyalgia syndrome. However, double-inhibition experiments revealed that both DNA and heparin can bind the enzyme in the presence of a bisubstrate analog (BiSA), and the binding of BiSA has a very weak synergistic effect on the binding of the second inhibitor (DNA or heparin) and vice versa.

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Teaching biochemistry at Lisbon University-Facing the challenge of the Bologna Declaration in the 25th anniversary of the biochemistry course. Phenelzine is thought to correct the biochemical defects caused by chronic cocaine use, namely the depletion of brain dopamine, norepinephrine, and serotonin. Ischemic heart disease complicated by heart failure: possibilities of surgical treatment

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Zori performs variational and diffusion Monte Carlo computations as well as correlated wave function optimization. Subsequent piperidine hydrolysis produced more frequent breaks of the phosphodiester bonds at guanine positions, thus forming alkali-labile sites. This allows a simultaneous measurement of intracellular and plasma membrane resident receptors. The R36S mutation in CRYGD identified in this Chinese family caused a nuclear golden crystal cataract phenotype not described before. A novel immunosuppressive agent, FN18-CRM9, known to specifically kill T cells with great potency, was evaluated in a transplant model.

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Clinical documentation sets share up to 24 comparable data elements with trial documentation. In 57 of the 59 malignancies (96.6 per cent) correctly diagnosed by FNAB the histological type of tumour was successfully identified. Subclinical forms of viral hepatitis in the course of immunoglobulin prophylaxis

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To address this intriguing issue, identifying the actual substrate for epoxidation and sequential cyclization is essential. These results integrate an increase in blood glucose after epinephrine release from the adrenal medulla with provision of brain energy substrates, including lactate released from astrocytes. Effect of traditionally used neem and babool chewing stick (datun) on streptococcus mutans: an in-vitro study. The signal-to-noise ratio is sufficiently good for further data treatment like multiple scattering deconvolution and Kramers-Kronig analysis. Results from a variety of complementary approaches, clearly demonstrate that the BglI element does not occur as a satellite-like repetitive DNA in these species but is part of the rDNA cistron as suggested by Goodier and Davidson (1993).

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The heterogeneous characteristics of trauma populations with respect to geography and mode of injury should be recognised in the planning of preventive strategies and in the organisation of trauma care. Acute and subchronic effects of amitriptyline on processing capacity in neuropathic pain patients using visual event-related potentials: preliminary findings.

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Toxicity of cadmium sulphate and methylmercuric chloride applied singly or in combination to early mouse embryos in vitro. The effects of titania nanotubes with embedded silver oxide nanoparticles on bacteria and osteoblasts. To compare dose and image quality of 64-slice, first and second generation dual-energy CT (DECT) for CT pulmonary angiography (CTPA).

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Bipolar depression remains a major unresolved challenge for psychiatric therapeutics. Toxicity of antihypertensives in unintentional poisoning of young children.

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Studies were initiated to investigate the similarities in alterations in cytochrome P450s (CYPs) and associated signaling events in brain and peripheral blood lymphocytes (PBL) induced by lindane, an organochlorine pesticide. Previous studies have suggested that these fractures are frequently not diagnosed and that radiologists miss a high percentage of osteoporotic, vertebral fractures present on lateral chest radiographs. A brief literature review and comparison to previously published cases of tracheal hypoplasia in other breeds is presented along with a description of a subaortic septal ridge and comparison to the analogous condition in humans. However, affinity constants for (3)H nisoxetine were found to be significantly higher in sensorimotor and/or prefrontal cortex of rats gonadectomized and gonadectomized and supplemented with estradiol for 4 or 28 days but similar to control in gonadectomized rats given testosterone.

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We evaluated goodness-of-fit, calibration and discrimination, and compared it with a model based on primary screening with FIT only. Terminal restriction fragments of telomere are detectable in plasma and their length correlates with clinical status of ovarian cancer patients. In this paper, we also highlight possible etiologic factors, presenting symptoms, diagnostic methods, and treatment modalities of CDF.

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This paper provides an overview of occupational therapy in the context of psychiatric rehabilitation and mental health recovery. Detection of residual and/or recurrent NPC has important clinical implications, as salvage protocols are available.

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Are there structural alterations in synapses related to functioning? Targeted routine antenatal anti-D prophylaxis in the prevention of RhD immunisation--outcome of a new antenatal screening and prevention program. A systematic literature search was performed in Medline and Embase in March 2014 without limits for publication date.

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