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Carbohydrate-remodelled acid alpha-glucosidase with higher affinity for the cation-independent mannose 6-phosphate receptor demonstrates improved delivery to muscles of Pompe mice. Analogy in moral deliberation: the role of imagination and theory in ethics. All patients were diagnosed according to the Diagnostic and Statistical Manual for Mental Disorders (DSM-IV) and were assessed by means of the STIPO.

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Smelling the diagnosis: a review on the use of scent in diagnosing disease. Our earlier experiments have shown that facilitating action of angiotensin II (AII) on recall of passive avoidance is mediated by dopaminergic systems. Cause and sequelae of intrapulmonary shadows in primary tuberculosis.

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Prolonged normovolemic hemodilution in therapy of patients with obliterating endarteritis of lower limb vessels However, understanding how antigens are delivered to follicular dendritic cells (FDC), which are the primary depot for B cell antigen within the lymph node follicles, is only recently beginning to be dissected. Recently, in addition to their role in enamel formation, the biological activity of enamel proteins in the process of cell differentiation has recently become widely appreciated. It integrates a set of tools for the analysis of fluorescence images from 3-D wide-field or confocal microscopy.

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This is the first report of human herpes simplex virus-1 encephalitis followed by urinary retention at early stage from the onset like the Elsberg syndrome. Mutation analysis of patients with neurodegenerative disorders using NeuroX array. FE is essential for the assessment of causal association between the exposure to specific agents and the occurrence of diseases. Determination by gel filtration of association constants for metal-nucleotide interaction. We recently described GPR54 as one of these proteins by genome mapping in a very informative family.

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To test whether the furrow was present or not only in PFR-bearing flagella, different protists containing or lacking the PFR, were analysed by AFM. Common presenting symptoms included irritability, tachycardia, and erythematous flushed skin. However, the normal cellular function of PrP(C) remains unclear.

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Furthermore, IGF-1 stimulated Kp release from POA/RHA incubated in vitro CONCLUSION: IGF-1 stimulates prepubertal Kp synthesis and release following activation of a mTOR signaling pathway and ALC blocks this pathway at the level of IGF-1R. Chimeragenesis, structure-guided mutagenesis, and directed evolution have proven effective strategies for tuning absorption wavelength, altering ion specificity and increasing fluorescence. The spectral interferences of the matrix of Dy on other REEs have been studied for a high resolution ICP-AES with a grating of 3600 grooves/mm. We investigated the range expansion histories of Machilus thunbergii populations in the Kinki region of central Japan on the basis of nuclear microsatellite data.

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The five dimensions of fatigue (General, Emotional, Physical, Mental, Vigor) found for Whites in prior research were not found for African-Americans in this study. The effect of pore size of the inhaler support upon the concentration of volatile drug emerging in the air stream from a nasal inhaler.

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They were found to be as sensitive as p53-positive transformed cells. The effect of occlusion therapy on motion perception deficits in amblyopia.

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In separate experiments, the accuracy of the model was verified with a survival cohort. Although the highest modulus of elasticity was found for the specimens laser-treated with 240 V, there were no significant differences in elastic modulus among 240 V, 300 V and Co-Cr.

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Headless, hungry, and unhealthy: a video content analysis of obese persons portrayed in online news. These results suggest that YAP promotes muscle differentiation by activating the Abl/Src/MEKK3/MEK5/ERK5 kinase cascade.-Chen, T.-H., Chen, C.-Y., Wen, H.-C., Chang, C.-C., Wang, H.-D., Chuu, C.-P., Chang, C.-H. Molecular genetic testing is essential for establishing the correct diagnosis in patients with NR2E3 mutations because of the variable phenotype associated with these degenerations. One way viruses achieve this is by modulating cell cycle progression.

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We aimed to assess the rates, reasons, and risk factors for 90-day re-admissions after total knee arthroplasty (TKA) in a European healthcare setting. Nicotinamide coenzyme concentrations in livers of normal, starved and alloxan-diabetic rats. Patients with dual diagnosis displayed a significantly elevated usage of all types of hospital contacts except inpatient treatment for non-psychiatric disorders. Lower uterine segment thickness measurement in pregnant women with previous caesarean section: intra- and interobserver reliability analysis using bi- and tridimensional ultrasonography

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After having administered the instrument six times they completed a third questionnaire that assessed their perceptions of the VQ-S based on their total experience. PET-computed tomography is useful in lymph node staging and targeted radiotracers are increasingly exploited as potential biomarkers of treatment response. The results show that the forward inclination of the trunk required when lower handlebars were used did not affect lumbar lordosis or thoracic kyphosis, but gave increased extension of the upper-cervical spine. Plasmodium berghei NK65 in the inbred A-J mouse: age immunity in the female retired breeder A-J mouse.

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This evidence-based guideline was developed using the Grading of Recommendations, Assessment, Development, and Evaluation approach to describe the strength of recommendations and the quality of evidence. Male sex, high initial sputum acid-fast bacilli grades, and cavitary diseases were factors associated with the 2-month positive smear and increasing risk of treatment failure. However, the procedures require extensive computerized planning. We first demonstrated that alterations in the balance of low to high frequency (LF/HF) changes in heart rate variability (a measure of baroreflex sensitivity) could account for some of the inflammation-evoked changes in diastolic blood pressure, indicating a central (rather than solely local endothelial) origin.

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On the factor producing agglutination of sensitized red cells and its relation to the agglutination of hemolytic streptococci in rheumatoid arthritis sera. The last approach described in our work of conjugation of a preformed chelate has advantages of characterizable 99mTc complex chemistry and conjugation by standard protein derivatization chemistry. Patients were identified by review of department billing records between 1995 and 2010.

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No attempts were made to assess their relative importance in the transmission of the disease, which in Britain is transmitted mainly by the rabbit flea. Recently, two studies have shown that the use ofgene-expression profiling using DNA microarrays or DNA chips may improve the classification of acute myeloid leukaemia (AML).

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Supporting the concurrent and convergent validity of the scale, the CET correlated in the expected direction with existing measures of excessive exercise and eating pathology. Alterations in platelet count and mean platelet volume as predictors of patient outcome in the respiratory intensive care unit. Identification of genetic polymorphisms through comparative DNA sequence analysis on the K-ras gene: implications for lung tumor susceptibility. alpha-D-Glucopyranose pentaacetate (1) was found to undergo stereoselective conversion in good yield into 3-(tetra-O-acetyl-alpha-D-glucopyranosyl)-1-propene (4) by treatment with allyltrimethylsilane and boron trifluoride etherate in acetonitrile.

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Ultrasound therapy was applied to all of the participants as a basic treatment. Qualitative differences in the behavior of pneumoncoccal deoxyribonucleic acids transforming to the same capsular type. The sequence of the cloned gene was found to be similar to that of the B. Changes in mean arterial pressure do not necessarily reflect corresponding changes in cardiac index.

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Three-dimensional CT pyelography for planning of percutaneous nephrostolithotomy: accuracy of stone measurement, stone depiction and pelvicalyceal reconstruction. The outcomes of critically ill patients who undergo interhospital transfer are not well understood. Radiation injuries often occur during or after radiation therapy in the abdomen or pelvis. Over the whole study period, mortality from alcoholic liver cirrhosis increased steeply.

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The mesolimbic dopamine pathway, which originates in the ventral tegmental area (VTA), is important for the rewarding effects of ethanol. This was diagnosed preoperatively and a scheme is suggested whereby such a disgnosis can now readily be made. Hydroxyapatite coating does not improve uncemented stem survival after total hip arthroplasty! These results suggest that there exists developmentally regulated silencing of pmeu1 by a heterologous PME antisense gene.

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Macrophages utilize the mitochondrial calcium uniporter for profibrotic polarization. Antibacterial peptide pleurocidin forms ion channels in planar lipid bilayers. Early detection of intermittent and potentially serious complications justifies routine use of this feature.

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Comfort and bleeding after percutaneous transluminal coronary angioplasty: comparison of a flexible sheath and a standard sheath. Moreover, this increase was found in relation with the severity of obstruction. Most of the radiographs performed in the intensive care unit exhibited no statistically significant clinical alterations, and the radiographs that revealed abnormalities did not necessarily lead to changes in medical care. It is concluded that antiestrogens do not act by simply competing with estrogen for receptor sites.

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Cheese wire fenestration of a chronic juxtarenal dissection flap to facilitate proximal neck fixation during EVAR. Volume measurements of intracerebral haemorrhage are prognostically important and are increasingly used in clinical trials to measure the effects of potential interventions.

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Mineral density of trabecular bone at the metaphyses of right tibiae was measured by peripheral quantitative computed tomography (pQCT) in ovariectomized rats. The Danish Civil Registration System, the Danish Cancer Registry and hospital-based registries were used to identify all patients resident in Greenland diagnosed with head and neck cancer during the period 1994-2003.

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This phenomenon did not appear in our material following lesions involving other structures e.g. Clinico-radiological considerations on postoperative peptic ulcer after gastric resection Successful application of thrombolysis and angioplasty in case of mechanical aortic valve and coronary graft thrombosis. Cell viability was tested by MTT.Expression and phosphorylation levels of proteins were detected by Western blotting. The only statistically significant differences were found at the age of 1 day, when the epidural group infants habituated and oriented better to inanimate auditory stimuli.

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It demonstrates that the Al2O3 films are successfully deposited onto the surface of PET films. Atropine inhibition of insulin-, histamine-, and pentagastrin-stimulated gastric electrolyte and pepsin secretion in the dog.

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Orthogonal test design for optimizing the extraction of total flavonoids from Inula helenium. The low-power manipulation of the magnetization, preferably at ultrashort timescales, has become a fundamental challenge with implications for future magnetic information memory and storage technologies. More than 300 mutations have been identified in five genes encoding key ion channel subunits. Balloon dilation is noninferior to FESS for symptom improvement and superior to FESS for postoperative debridements in patients with maxillary and anterior ethmoid disease.

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Routine bronchoscopy (without endobronchial application of LFUS and UVLR) was included into the treatment of 47 patients with CB and BD. Common symptoms can include dysphagia, dry mouth, decreased taste, and tooth decay. Currently, there are no data on smear-negative pulmonary TB cases in prisons and by extension no data on the impact such cases have on TB incidence. Chronic cocaine users accurately reported total sleep time after 1 week of abstinence but overreported total sleep time by an average of 40 min after 2 weeks of abstinence. This work presents the fabrication of a microfluidic autoregulatory valve which is composed of several layers of thin polymer films (i.e., polyvinyl chloride (PVC), polyethylene terephthalate (PET) double-sided tape, and polydimethylsiloxane (PDMS)).

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Cross-sectional analytical study using medical records from February 2010 to April 2016. HOPX-specific knockdown decreased HOPX expression in the nonmetastatic subclone and displayed reduced cell motility in vitro. Separating historic events from recurrent processes in cryptic species: phylogeography of mud snails (Hydrobia spp.). sai1 is allelic to npr1, a previously identified SA-noninducible mutation.

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Few individuals with spinal cord injury (SCI) engage in the recommended amount of leisure time physical activity (LTPA). The following parameters were investigated: type, duration and frequency of infections, bacterial colonisation and serum levels of IgG to bacteria, serum levels of total Ig, plasma cytokine levels, granulocyte reactive oxygen species production, lysozyme activity and phagocytosis. Combined Treatment of Androgen-Independent Prostate Cancer Cell Line DU145 with Chemotherapeutic Agents and Lithium Chloride: Effect on Growth Arrest and/or Apoptosis. Cancer radiotherapy and chemotherapy created an immunosuppressed state, which allowed the development of herpes zoster ophthalmicus.

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vaginalis that were radiolabeled and assayed for chemotaxis in plastic multiwelled plates with a membrane filter inserted to trap organisms, the response of clinical isolates to various antimicrobial agents was studied. Data are discussed on the basis of the interactions between the noradrenergic and serotonergic systems in the mediation of the facilitatory effect of 8-OH-DPAT in sexually exhausted and non-exhausted rats.

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Better results were achieved using a silicone-based soft liner, which recommends it as the material of choice for relining dentures. Due to the limited availability and morbidity associated with autologous tissue donor sites, the introduction of regenerative medicine has been critical in managing war extremity injuries with composite massive tissue loss. The procedure has been safely adopted by surgeons who frequently perform laparoscopies. Computerized nuclear morphometry and quantitation of angiogenesis in thyroid neoplasms. ROS may act as a retrograde signal, regulating the cell response.

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Other studies indicated that lung cancer may have biological characteristics and mechanisms of carcinogenesis that are gender specific. Muscarinic receptor modulation of basal and beta-adrenergic stimulated function of the failing human left ventricle. Finally, we show that the main structural fluctuations that affect water reorientation dynamics in the bulk are angular distortions, which we explain by the jump hydrogen-bond exchange mechanism.

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Even localized ESCC are potential to relapse with poor prognosis. It is crucial for any register to obtain a high accuracy in order to be a credible and reliable source for quality evaluation, research, and development.

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Twenty-two children with absence epilepsy aged 8-17 years underwent comprehensive neuropsychological evaluation including EpiTrack Junior and measures of intelligence, verbal and nonverbal memory, word fluency and visuoconstructive organization. Calpain was also required for the microtubule-mediated turnover of adhesive complex sites after nocodazole wash-out, suggesting that calpain may mediate focal complex disassembly downstream of microtubules. The infection was acquired in the Netherlands and not abroad, considering the incubation period.

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However, IPC, another effective method to prevent hepatic IR injury, might exacerbate liver tumor growth. The purpose of this study was to evaluate the impact of exogenous surfactant on the duration of extracorporeal membrane oxygenation needed to support neonates. We also compared practices based in Europe in 60 respondents and in the United States in 70.

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Electronic and molecular structures of trans-dioxotechnetium(V) polypyridyl complexes in the solid state. Developmental changes in rat adrenal tyrosine hydroxylase, dipamine- -hydroxylase and catecholamine levels: effect of denervation. Cadmium (Cd) induces necrotic death in Chinese hamster ovary (CHO) K1 cells and we have established the responsible signaling pathway. The capping protein on the slow-growing end of actin filament: erythrocyte tropomodulin Pharmacological researches revealed that perampanel reduces neuronal excitability by a non-competitive antagonistic activity against the ionotropic alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors causing modulation of glutamatergic neurotransmission.

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All participants reduced gait asymmetry and improved on outcomes at posttest and follow-up. There were no group differences in learning the alternation rule or at short intervals, but obese rats were impaired at longer intervals where performance is hippocampus dependent. The L11-deficient embryos (morphants) displayed developmental abnormalities primarily in the brain, leading to embryonic lethality within 6-7 days post fertilization. The importance of recognizing a possible association between these two conditions is discussed.

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Serum gonadotropin responses to estrogen and progestogen in recently castrated human females. Three examinees ultimately passed this assessment and were assigned as new Japanese astronaut candidates. Homeopathy is a medical discipline in its own right which is quite different from orthodox medicine in its basic tenets, its research paradigms and its practical approach to therapy, even though both methods are empirically founded and share the aim of healing the sick.

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These measurements were made at different times: before the transplant, 48 h after the transplant, a week after the transplant and two weeks after the transplant. An inverse association between serum leptin concentration and reported alcohol intake in patients with manifest vascular disease. The experimental results are consistent with the theoretical model in a previous study. Patients with compression of the celiac axis by the median arcuate ligament may develop aneurysms in the pancreaticoduodenal arcades.